“The Strain is a bloody, gruesome, often scary vampire thriller that benefits from del Toro's visual flair and a strong cast. It's not subtle, but it doesn't need to be.”
Tim Goodman
The Hollywood Reporter

Guillermo del Toro and Carlton Cuse brought a fresh, visceral take on vampire mythology to FX with The Strain, which ran from 2014 to 2017 across four seasons and 46 episodes. The show follows Dr. Ephraim Goodweather (Corey Stoll), head of the CDC's Canary Team in New York City, as he investigates a bizarre viral outbreak that turns out to be an ancient vampiric strain. Unlike romanticized vampires, these creatures are parasitic, worm-tongued monsters that spread like a plague. The ensemble includes Kevin Durand as exterminator Vasiliy Fet, David Bradley as Holocaust survivor and vampire hunter Professor Abraham Setrakian, and Miguel Gómez as streetwise Gus Elizalde. With a tone blending body horror, conspiracy thriller, and apocalyptic drama, the series earned a dedicated fanbase and solid ratings for its relentless pacing and practical effects. It's a gritty, no-nonsense horror show that treats vampirism as a biological and existential threat.
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A Boeing 777 lands at JFK and goes dark. All window shades are drawn, the lights are off, and every communication channel is dead. The CDC dispatches Dr. Ephraim Goodweather and his colleague Nora Martinez to investigate. Inside, they find nearly everyone dead except four survivors. The passengers appear to have died from a rapid-acting pathogen, but the symptoms don't match any known disease.
As Eph and Nora try to contain what they think is a virus, they cross paths with Abraham Setrakian, an elderly pawnshop owner who immediately recognizes the truth. Setrakian is a Holocaust survivor who first encountered these creatures in a Nazi concentration camp, where a sadistic officer named Thomas Eichorst served an ancient vampire known only as the Master. The infection is not a virus but a parasitic organism transmitted through a long, retractable stinger that emerges from the mouth. The infected transform into strigoi: pale, hairless, clawed beings with red eyes, superhuman strength, and a vulnerability to sunlight.
The outbreak spreads through New York City with terrifying speed. Eph teams up with Setrakian, rat exterminator Vasiliy Fet, and streetwise kid Gus Elizalde to fight back. They discover that the Master has orchestrated the outbreak as part of a centuries-old plan to conquer humanity. The Master is aided by billionaire Eldritch Palmer, who traded his humanity for immortality, and Eichorst, who serves as his lieutenant. Complicating everything, Eph is locked in a custody battle with his ex-wife Kelly over their son Zach. When Kelly becomes infected, Zach is caught between his father's desperate protection and his mother's transformation into a strigoi.
Season 1 establishes the outbreak and the initial response, ending with a failed assault on the Master's lair. Season 2 expands the scope as the city falls. The resistance develops a silver-based bioweapon while Setrakian searches for the Occido Lumen, a book containing the secrets to killing the Master. New allies join: hacker Dutch Velders and Mr. Quinlan, a Born strigoi who has hunted the Master for millennia. Season 3 turns New York into a battleground. The group splinters under betrayal and paranoia, and they discover a nuclear weapon as a potential final solution. Season 4 jumps nine months into a world where the strigoi have won. The Master has established the Partnership, forcing humans to collaborate or die. The resistance, now a shadow of its former self, must make a desperate final stand with the nuclear bomb.
Official Series Trailer
The Strain Trailer
Critical Consensus
The Strain received generally favorable reviews for its ambitious scope, practical effects, and del Toro's distinctive visual style, though critics noted uneven pacing, inconsistent character development, and a tonal struggle between serious horror and camp. The series was praised for its fresh take on vampire mythology but criticized for losing narrative momentum in later seasons. Its body horror elements and committed performances, particularly from David Bradley and Kevin Durand, were consistently highlighted as strengths.
“The Strain is a bloody, gruesome, often scary vampire thriller that benefits from del Toro's visual flair and a strong cast. It's not subtle, but it doesn't need to be.”
Tim Goodman
The Hollywood Reporter
“Del Toro and Cuse have crafted a show that moves at a brisk pace and doesn't shy away from the ick factor. The Strain is a B-movie elevated by its pedigree.”
Brian Lowry
Variety
“The Strain works best when it leans into its pulpy, gross-out roots and worst when it tries to be a prestige drama. Corey Stoll is excellent, but the show's real MVP is David Bradley's Setrakian.”
Alan Sepinwall
HitFix
“Guillermo del Toro's vampire series is a messy, entertaining, and occasionally ridiculous horror show that knows exactly what it wants to be: a gross-out, action-packed B-movie stretched to series length.”
Mike Hale
The New York Times
Director
Guillermo del Toro
Writers
Guillermo del Toro, Chuck Hogan, Carlton Cuse, Regina Corrado, David Weddle, Bradley Thompson, Liz Phang
Composer
Ramin Djawadi
Producers
Carlton Cuse, Guillermo del Toro, Chuck Hogan
Primetime Emmy Award for Outstanding Prosthetic Makeup for a Series, Limited Series, Movie or Special (2015)
Prosthetic Makeup: Nominated
Primetime Emmy Award for Outstanding Prosthetic Makeup for a Series, Limited Series, Movie or Special (2016)
Prosthetic Makeup: Nominated
Canadian Screen Award for Best Visual Effects (2016)
Visual Effects: Won
Saturn Award for Best Horror Television Series (2015)
Television: Nominated
Saturn Award for Best Actor on Television (2015)
Television: Nominated
Saturn Award for Best Supporting Actress on Television (2015)
Television: Nominated
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